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New strategy to attack tumor-feeding blood vessels

Scientists at the Walter and Eliza Hall Institute have discovered a key molecule needed to kill the blood vessels that supply tumours.

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Researchers discover potential new mechanisms of drug resistance in Toxoplasma

Scientists have for years been puzzled by why drugs are sometimes effective in treating parasitic diseases, while other times they have little or no effect.

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Club cells are 'bad guys' during flu infection

A specialized subset of lung cells can shake flu infection, yet they remain stamped with an inflammatory gene signature that wreaks havoc in the lung, according to a study published in The Journal of...

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Commentary focuses on 2014 Ebola outbreak in west africa

(HealthDay)—The Ebola epidemic is spreading in West Africa, with little hope for treatment, and an experimental therapy is unlikely to be provided to African patients, according to two commentaries...

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Potential therapy for incurable Charcot-Marie-Tooth disease

Charcot-Marie-Tooth disease type 1A is the most common inherited disease affecting the peripheral nervous system. Researchers from the Department of Neurogenetics at the Max Planck Institute of...

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Unusual immune cell needed to prevent oral thrush

An unusual kind of immune cell in the tongue appears to play a pivotal role in the prevention of thrush, according to the researchers at the University of Pittsburgh School of Medicine who discovered...

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T-bet tackles hepatitis

A single protein may tip the balance between ridding the body of a dangerous virus and enduring life-long chronic infection, according to a report appearing in The Journal of Experimental Medicine.

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New rules for anticancer vaccines

Scientists have found a way to find the proverbial needle in the cancer antigen haystack, according to a report published in The Journal of Experimental Medicine.

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'JAKing' up blood cancers, one cell at a time

A solitary cell containing a unique abnormality can result in certain types of blood cancers known as myeloproliferative neoplasms (MPN), according to a study published in The Journal of Experimental...

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How Staph infections elude the immune system

A potentially lethal bacterium protects itself by causing immune tunnel vision, according to a study from scientists at The University of Chicago published in The Journal of Experimental Medicine. By...

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Synapses always on the starting blocks

While neurons rapidly propagate information in their interior via electrical signals, they communicate with each other at special contact points known as the synapses. Chemical messenger substances,...

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Study suggests how flu-related gastrointestinal flare-ups can be relieved...

Flu infection has long-ranging effects beyond the lung that can wreak havoc in the gut and cause a dreaded symptom, diarrhea, according to a study published in The Journal of Experimental Medicine.

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Immunotherapy for cancer toxic with obesity: Researchers link increased body...

Immunotherapy that can be effective against tumors in young, thin mice can be lethal to obese ones, a new study by UC Davis researchers has found. The findings, published online today in The Journal of...

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Infection-fighting B cells go with the flow

Newly formed B cells take the easy way out when it comes to exiting the bone marrow, according to a study published in The Journal of Experimental Medicine.

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Drug injection protects monkeys from vaginal HIV infection

A monthly injection of an experimental anti-retroviral drug protected female monkeys from vaginal infection by a simian form of HIV, according to two new studies.

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Hemin improves adipocyte morphology and function by enhancing proteins of...

Scientists at the University of Saskatchewan College of Medicine, Department of Physiology, Saskatoon, Canada, led by Dr. Joseph Fomusi Ndisang have determined that upregulating heme-oxygenase with...

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Promising new strategy to halt pancreatic cancer metastasis

Pancreatic cancer and its metastases might have their days numbered, according to a study published in The Journal of Experimental Medicine.

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One step closer to defeating Alzheimer's disease

Tackling brain inflammation ameliorates Alzheimer's disease (AD), according to a study published in The Journal of Experimental Medicine.

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Veterinary researcher validates human tracheal/bronchial-cell model for...

A recently hired veterinary pathologist is bringing multiple skills to her new position in the College of Veterinary Medicine at Kansas State University, including experience with a human primary cell...

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Malarial parasites dodge the kill

Scientists have uncovered a potential mode of parasite drug resistance in malaria infection, according to a report published in The Journal of Experimental Medicine.

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